Imaging & Screening

Health Topics

Imaging & Screening

Blood tests tell you about chemistry. Imaging tells you about structure. Both are necessary for a complete picture of health risk.

Imaging studies provide structural and compositional data that blood tests cannot. A CAC scan reveals calcified plaque in coronary arteries. A carotid ultrasound detects early atherosclerosis. A DEXA scan measures visceral fat and lean mass. A FibroScan assesses liver health. Together, these tools identify risk factors that are invisible to standard lab work.

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Experts, Books & Resources

The physicians, researchers, books, and podcasts that inform this topic.

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CAC Scan — Coronary Artery Calcium

A Coronary Artery Calcium (CAC) scan is a low-dose CT scan that measures calcified plaque in the coronary arteries. It is one of the most powerful cardiovascular risk stratification tools available — providing a direct, structural measurement of atherosclerosis rather than a statistical prediction.

A CAC score of 0 is highly reassuring and associated with very low near-term cardiovascular event risk, even in the presence of elevated LDL or ApoB. A score above 100 significantly changes risk stratification and often influences decisions about statin therapy, aspirin, and lifestyle interventions.

  • CAC = 0: Very low near-term risk. Retest in 3–5 years.
  • CAC 1–99: Mild plaque. Lifestyle optimization is the priority.
  • CAC 100–399: Moderate risk. Discuss pharmacotherapy with your physician.
  • CAC ≥400: High risk. Aggressive intervention warranted.
  • Involves a small amount of radiation (~1 mSv). Requires physician order in most states.

Carotid Ultrasound (CIMT)

Carotid Intima-Media Thickness (CIMT) uses ultrasound to measure the thickness of the inner two layers of the carotid artery wall. It is non-invasive, involves no radiation, and can detect early atherosclerosis before it becomes symptomatic.

CIMT is particularly valuable for younger individuals where CAC may still be zero but early arterial changes are developing. It can also detect soft (non-calcified) plaque that CAC scanning misses. The combination of CAC and CIMT provides a more complete picture of arterial health than either test alone.

DEXA Scan — Body Composition

A DEXA (Dual-Energy X-ray Absorptiometry) scan is the gold standard for body composition assessment. It measures lean mass, fat mass, and bone density separately — and critically, it quantifies visceral fat, the metabolically active fat surrounding internal organs.

Visceral fat is a key driver of insulin resistance, inflammation, and cardiovascular risk. It is not captured by weight, BMI, or waist circumference alone. A DEXA scan provides precise, reproducible measurements that allow you to track changes in body composition over time.

FibroScan — Liver Health

FibroScan uses ultrasound-based technology to assess liver stiffness (a marker of fibrosis) and liver fat content (steatosis). It is non-invasive and can detect early non-alcoholic fatty liver disease (NAFLD/MASLD) before it progresses to fibrosis, cirrhosis, or liver failure.

NAFLD is now estimated to affect 25–30% of adults in developed countries — most of whom are unaware. It is closely linked to insulin resistance and metabolic syndrome. FibroScan provides early detection that standard liver enzyme tests (ALT, AST) often miss.

Continuous Glucose Monitor (CGM)

While not traditional imaging, a CGM provides real-time glucose data that reveals patterns invisible to fasting glucose and HbA1c — including post-meal spikes, overnight glucose trends, and glucose variability.

Even a 2–4 week CGM trial can provide significant insight into how specific foods, meals, sleep quality, and stress affect glucose regulation. This information is actionable in ways that quarterly HbA1c measurements are not.

Key Takeaways

  • CAC = 0 is highly reassuring even with elevated ApoB or LDL
  • CIMT detects soft plaque and early atherosclerosis without radiation
  • DEXA measures visceral fat — a key metabolic risk marker not captured by BMI
  • FibroScan detects early fatty liver disease before standard liver enzymes become abnormal
  • CGM reveals glucose patterns that fasting glucose and HbA1c miss entirely
  • Imaging and blood tests are complementary — both are needed for a complete picture

Labs & Testing

Key Markers to Know

These are the tests most relevant to this topic. Many are not included in standard panels — you may need to request them specifically.

CAC Score

Optimal: 0

Direct measure of coronary plaque. CAC = 0 is highly reassuring even with elevated ApoB.

CIMT

Optimal: <0.7 mm

Carotid artery wall thickness. Detects early atherosclerosis without radiation.

Visceral Fat (DEXA)

Optimal: Low risk zone

Visceral fat drives insulin resistance and cardiovascular risk. Not captured by BMI.

Lean Mass Index

Optimal: Age-appropriate

Muscle mass is a key longevity marker. DEXA provides precise measurement.

Liver Stiffness (FibroScan)

Optimal: <7 kPa

Marker of liver fibrosis. Elevated values indicate progressive liver damage.

CAP Score (FibroScan)

Optimal: <248 dB/m

Controlled Attenuation Parameter — measures liver fat content.

Disclaimer: All content is for educational and informational purposes only. It does not constitute medical advice and should not be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before making changes to your health plan.